Insider Transactions

Date	Name	Title	Filing	Type	Shares Traded	Price	Total Held
Dec 11, 2025	MURPHY ANDREW J EVP Research	EVP Research	Form 4	Other acquisition or disposition	--	--	4,375
Dec 09, 2025	MURPHY ANDREW J EVP Research	EVP Research	Form 4	Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3	4,229	$701.51	47,833
Dec 09, 2025	MURPHY ANDREW J EVP Research	EVP Research	Form 4	Other acquisition or disposition	--	--	4,375
Dec 08, 2025	MURPHY ANDREW J EVP Research	EVP Research	Form 4	Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3	1,699	$712.94	52,062
Dec 05, 2025	MURPHY ANDREW J EVP Research	EVP Research	Form 4	Grant, award or other acquisition pursuant to Rule 16b-3(d)	3,715	--	53,761
Dec 05, 2025	MURPHY ANDREW J EVP Research	EVP Research	Form 4	Grant, award or other acquisition pursuant to Rule 16b-3(d)	18,315	--	18,315
Oct 31, 2025	MURPHY ANDREW J EVP Research	EVP Research	Form 4	Other acquisition or disposition	--	--	4,370
Oct 30, 2025	MURPHY ANDREW J EVP Research	EVP Research	Form 4	Bona fide gift	1,538	--	50,046
Oct 29, 2025	MURPHY ANDREW J EVP Research	EVP Research	Form 4	Exercise or conversion of derivative security exempted pursuant to Rule 16b-3	35,000	$555.67	84,074
Oct 29, 2025	MURPHY ANDREW J EVP Research	EVP Research	Form 4	Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3	32,490	$648.82	51,584

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.