Insider Transactions

Date	Name	Title	Filing	Type	Shares Traded	Price	Total Held
May 16, 2024	YANCOPOULOS GEORGE Director, Bd. Co-Chair, President & CSO Trans History: 698	Director, Bd. Co-Chair, President & CSO	Form 4	Open market or private sale of non-derivative or derivative security	790	$972.22	812,381
May 16, 2024	YANCOPOULOS GEORGE Director, Bd. Co-Chair, President & CSO Trans History: 698	Director, Bd. Co-Chair, President & CSO	Form 4	Open market or private sale of non-derivative or derivative security	2,653	$973.80	809,728
May 16, 2024	YANCOPOULOS GEORGE Director, Bd. Co-Chair, President & CSO Trans History: 698	Director, Bd. Co-Chair, President & CSO	Form 4	Open market or private sale of non-derivative or derivative security	7,611	$974.51	802,117
May 16, 2024	YANCOPOULOS GEORGE Director, Bd. Co-Chair, President & CSO Trans History: 698	Director, Bd. Co-Chair, President & CSO	Form 4	Open market or private sale of non-derivative or derivative security	9,242	$975.48	792,875
May 16, 2024	YANCOPOULOS GEORGE Director, Bd. Co-Chair, President & CSO Trans History: 698	Director, Bd. Co-Chair, President & CSO	Form 4	Open market or private sale of non-derivative or derivative security	4,886	$976.52	787,989
May 16, 2024	YANCOPOULOS GEORGE Director, Bd. Co-Chair, President & CSO Trans History: 698	Director, Bd. Co-Chair, President & CSO	Form 4	Open market or private sale of non-derivative or derivative security	1,227	$977.38	786,762
May 16, 2024	YANCOPOULOS GEORGE Director, Bd. Co-Chair, President & CSO Trans History: 698	Director, Bd. Co-Chair, President & CSO	Form 4	Open market or private sale of non-derivative or derivative security	379	$978.18	786,383
May 15, 2024	SCHLEIFER LEONARD S Director, Bd. Co-Chair, President & CEO Trans History: 456	Director, Bd. Co-Chair, President & CEO	Form 4	Open market or private sale of non-derivative or derivative security	7,864	$979.05	400,336
May 15, 2024	SCHLEIFER LEONARD S Director, Bd. Co-Chair, President & CEO Trans History: 456	Director, Bd. Co-Chair, President & CEO	Form 4	Open market or private sale of non-derivative or derivative security	295	$980.64	400,041
May 15, 2024	SCHLEIFER LEONARD S Director, Bd. Co-Chair, President & CEO Trans History: 456	Director, Bd. Co-Chair, President & CEO	Form 4	Open market or private sale of non-derivative or derivative security	1,081	$981.50	398,960

* Represents the number of non-derivative securities directly held. (I) Indicates that some (or all) of these shares are held indirectly.